Talk:Ibritumomab tiuxetan
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[edit] Clean!
I have now fixed the grammar mistakes and cleaned this article. I have also put it in the correct category. (72.136.49.4 00:22, 28 December 2005 (UTC))
- Thank you!!! TestPilot 14:11, 28 December 2005 (UTC)
[edit] Pronunciation
I think it is pronounced EYE-bri-TOOM-oh-mab, not IH-bri-TOOM-oh-mab. Regards, Blake3522 11:45, 20 July 2007 (UTC)
I've worked on the drug at Biogen Idec for 5+ years, and I've never heard anyone call it anything but IH-bri-TOOM-oh-mab, defined as the mouse antibody without the chelator, tiuxetan. Ibritumomab tixuetan is the antibody+chelator, and when it has an isotope bound to the chelator it becomes either 111In-ibritumomab tixuetan or 90Y-ibritumomab tixuetan. (Or you can just do what we do, and call it all Zevalin.)Wsaville (talk) 18:11, 16 January 2008 (UTC)
[edit] Circular Link
Hi. I've removed the link to ibritumomab, which merely redirects back to this very page. The pronunciation is from an AOL site, I hope that's okay. I asssume they have (or had) the money to do it right, all else about AOL aside. Kenmcl2 15:20, 27 July 2007 (UTC)
[edit] two different drugs
Hi.
In-111 Zevalin and Y-90 Zevalin are two different drugs. The terms "Zevalin" or "Ibritumomab tiuxetan" by themselves do not precisely refer to RIT. They are the cold antibody without the radioactive molecule attached.
Since yttrium emits pure beta radiation, it cannot be used to get a picture with a gamma camera. So the indium version is used instead for the pretreatment image (taken about one week before the tx day). Indium emits some gamma along with beta.
The image is taken to make sure that the drug will go to where it should, and not go to where it shouldn't (e.g., excess amounts to marrow, liver, etc)
Kenmcl2 15:47, 27 July 2007 (UTC)
