Talk:Hyperkalemia
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Information from Hyperkalemia appeared on Portal:Medicine in the Did you know section on July 18, 2006. |
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[edit] What
What about calculating TTKG to aid in the differential diagnosis? Cybergoth 12:18, 27 August 2005 (UTC)
- Put it in. alteripse 21:34, 27 August 2005 (UTC)
Yes, that would be useful. Here is an online calculator. JFW | T@lk 23:08, 27 August 2005 (UTC)
Deleted "Liddles Syndrome" & "Pseudohyperaldosteronism" from the Differential Diagnosis, since those are associated with HYPOkalemia. 129.22.127.147 02:51, 10 March 2006
- Good pick up. Andrew73 13:19, 10 March 2006 (UTC)
I like that "lethal injection" is listed under "causes include:" :-) Mbarbier 17:48, 8 November 2007 (UTC)
- I agree that its very wierd (and funny) to have "lethal injection" there. But really, its probably the best place for it, rather than creating a separate section for it. :-) Dan Levy 19:40, 8 November 2007 (UTC)
[edit] hyperkalemia wrong information in article
Increased extracellular potassium will cause hyperpolarization and not depolarization of the cell membrane. dont you agree?
Disagree: Imagine a typical cell which has a membrane voltage determined predominately by conductance through potassium channels. The point of equilibrium (where the membrane potential will equilibrate) is the Nernst potential for K, which equals -60mV*Log([K]i/[K]o). As [K]o rises, the membrane will equilibrate at a less negative potential. Hence, the cell will be depolarized in the setting of hyperkalemia. DanLevy 04:53, 10 June 2006 (UTC)
[edit] +
Will delete comment by user 85.167.25.246 regarding Hyperkalemia causing acidosis. True that cardiac arrest, or weakness of diaphragmatic muscles could lead to hypoxia/ischemia that would cause acidosis, but I think that these would be extreme examples, and the statement is otherwise misleading. Dan Levy 03:26, 12 December 2006 (UTC)
Jan 11th, 2007
Changed the phrase: Potassium is the most important intracellular cation and participates in many cellular processes to Potassium is an important intracellular cation and participates in many cellular processes.
I don't think you can establish that K+ is the most important intracellular cation, considering the important of Na+ and Ca2+.
- ......JFW has reverted the sentence, but I agree with the above author....Is the heart or the brain the most important organ? Without intracellular calcium, none of our cells would work either. Abundance is irrelevant. How about we settle on "a critically important cation."Dan Levy 02:52, 12 January 2007 (UTC)
[edit] Pseudohyperkalemia
I deleted the phrase: "It can be avoided by using plasma from anticoagulated blood samples, as this will reduce the destruction of cells and platelets during the clotting process." because I think that it was misleading. It was located right after mentioning the familial pseudohyperkalemias. In fact, in ref 3 (Blood, 1999) the heparinized blood that incubates for a few hrs shows increased serum [K] over time. But I think that the statement might apply for thrombocytosis and perhaps it should simply be moved to a different position in the paragraph? I assume that the best strategy for any suspected case of pseudohyperkalemia would be to spin anticoagulated blood immediately and measure the K from the plasma. I know that plasma K is always a bit lower than serum K, but would user 205.160.195.36 be able to offer a reference that anticoagulation would specifically be helpful when pseudohyperkalemia is suspected? Dan Levy 22:59, 19 June 2007 (UTC)
- I think you are correct to have removed it, but would defer to an explicit reference. alteripse 00:04, 20 June 2007 (UTC)
