HLA-B42

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major histocompatibility complex (human), class I, B42
Alleles B*4201
B*4202
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*4201
EBI-HLA B*4202
Locus chr.6 6p21.31

HLA-B42 (B42) is an HLA-B serotype. The serotype identifies the HLA-B*4201 and *4202 gene products.[1] HLA-B*4201 is common Central Africa. (For terminology help see: HLA-serotype tutorial)

[edit] Serotype

B42 serotype recognition of Some HLA B*42 allele-group gene products[2]
B*42 B42 other Sample
allele  %  % size (N)
4201 93 2 1015
4202 95 80

Serological typing for B*4201 and B*4202 is relatively efficient.


[edit] B*4201 allele frequencies

HLA B*4201 frequencies
freq
ref. Population (%)
[3] Zambia Lusaka 14.8
[3] Mali Bandiagara 13.8
[3] Burkina Faso Mossi 13.2
[3] South Africian Natal Zulu 12.0
[3] Burkina Faso Rimaibe 9.6
[3] South Africa Tswana 8.5
[3] Kenya Luo 7.7
[3] Kenya 7.3
[3] Kenya Nandi 6.9
[3] Zimbabwe Harare Shona 6.9
[3] Saudi Arabia 5.6
[3] Cameroon Yaounde 4.9
[3] Cameroon Beti 4.0
[3] Cameroon Bamileke 3.9
[3] Cameroon Sawa 3.8
[3] Ivory Coast Akan Adiopodoume 3.4
[3] Israel Gaza Palestinians 2.4
[3] India North Delhi 2.2
[3] Senegal Niokholo Mandenka 1.6
[3] Mbenzele Pygmy (C. Afr. Rep.) 1.5
[3] Iran Baloch 1.5
[3] Pakistan Baloch 1.5
[3] Sudanese 1.5
[3] Tunisia 1.5
[3] Pakistan Brahui 1.4
[3] Cameroon Bamileke 1.3
[3] Oman 1.3
[3] Sudanese 1.3
[3] Tunisia Tunis 1.1
[3] Zimbabwe Harare Shona 1.1
[3] Cameroon Bakola Pygmy 1.0
[3] Pakistan Pathan 1.0
[3] Portugal Centre 1.0
[3] Saudi Arabia Guraiat and Hail 1.0
[3] Morocco Casablanca 0.9
[3] Senegal Dakar 0.9
[3] Uganda Kampala 0.9
[3] Cape Verde Southeastern Islands 0.8
[3] Guinea Bissau 0.8
[3] United Arab Emerates 0.8
[3] Morocco Nador Metalsa Class I 0.7
[3] Pakistan Karachi Parsi 0.6
[3] Spain Majorca 0.6
[3] China Yunnan Han pop2 0.5
[3] England Newcastle 0.5
[3] Israel Arab Druse 0.5
[3] Israel Jews 0.5
[3] Italy Rome 0.5
[3] Guadalajara Mestizos (2) (Mexico) 0.5
[3] Morocco 0.5
[3] Pakistan Sindhi 0.5
[3] Senegal Niokholo Mandenka 0.5
[3] Singapore Riau Malay 0.5

[edit] References

  1. ^ Marsh SG, Albert ED, Bodmer WF, et al (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720. 
  2. ^ derived from IMGT/HLA
  3. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. PMID 12753660. 
v • d • e
HLA-B serotypes and allele groups

HLA-B · B5 (B51 · B52) · B7 · B8 · B12 (B44 · B45) · B13 · B14 (B64 · B65) · B15 (B62 · B63 · B70 · B71 · B75 · B76 · B77) · B16 (B38 · B39) · B17 (B57 · B58) · B18 · B21 (B49 · B50) · B22 (B54 · B55 · B56) · B27 · B35 · B37 · B40 (B60 · B61) · B41 · B42 · B46 · B47 · B48 · B53 · B59 · B67 · B73 · B78 · B81 · B*82 · B*83