Heteroglycan alpha-mannosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a heteroglycan alpha-mannosyltransferase (EC 2.4.1.48) is an enzyme that catalyzes the chemical reaction

GDP-mannose + heteroglycan GDP + 2(or 3)-alpha-D-mannosyl-heteroglycan

Thus, the two substrates of this enzyme are GDP-mannose and heteroglycan, whereas its 3 products are GDP, 2-alpha-D-mannosyl-heteroglycan, and 3-alpha-D-mannosyl-heteroglycan.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase. Other names in common use include GDP mannose alpha-mannosyltransferase, and guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase.

[edit] References

• IUBMB entry for 2.4.1.48
• BRENDA references for 2.4.1.48 (Recommended.)
• PubMed references for 2.4.1.48
• PubMed Central references for 2.4.1.48
• Google Scholar references for 2.4.1.48
• Garancis JC, Ankel H, Ankel E, Schutzbach JS (1970). "Mannosyl transfer in Cryptococcus laurentii". J. Biol. Chem. 245: 3945–55. PMID 5492958. 

[edit] External links

The CAS registry number for this enzyme class is 37277-57-9.

• IUBMB entry for 2.4.1.48

• KEGG entry for 2.4.1.48

• BRENDA entry for 2.4.1.48

• NiceZyme view of 2.4.1.48

• EC2PDB: PDB structures for 2.4.1.48

• PRIAM entry for 2.4.1.48

• PUMA2 entry for 2.4.1.48

• IntEnz: Integrated Enzyme entry for 2.4.1.48

• MetaCyc entry for 2.4.1.48

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047264: heteroglycan alpha-mannosyltransferase

• AMIGO entry for GO code 0047264: heteroglycan alpha-mannosyltransferase