Talk:Herpes simplex virus

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Reference 20 quotes itself when you open the link, I looked into this link as the content is not credible for content, then I find that it quotes itself, further to being non-credible.
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[edit] "Crudescent?"

From the article, "Lesions heal with a crudescent scab." What does crudescent mean? It's not in the dictionary at dictionary.com nor wiktionary nor Answers.com, and most Google results are simply variations on that phrase. 68.36.163.22 05:35, 17 August 2007 (UTC)

[edit] Proposed section merges/article deletion

The dual coverage of Herpes Simplex Virus (this article) vs. Herpes Simplex Disease, in addition to the article Herpesviridae, is not working out as well as I had hoped. I previously argued for the maintenance of two articles, one for the disease, the other for the virus -- similar to the two articles maintained for AIDS and HIV. However, in the case of Herpes, the similarity of naming is part of the difficulty in maintaining two independent articles.

Here is my view of this articles sections:

  • Intro
At present, this article's introductory material is largely repetitive of the information from the disease article, and should be merged to the disease article or deleted.
  • Life cycle
This information is true for all Herpes viruses and belongs in Herpesviridae.
  • Treatment
The information here that relates treatment mechanism to viral biology belongs in Herpesviridae. Epidemiological information belongs in Herpes Virus.
  • Vaccine
This little section should merge with the disease article.

I think the original intent of these two article will be better served if Herpes virus information is accumulated at the Herpesviridae article. The technical-sounding name there will discourage general disease information being added. I have added merge tags in the hope of generating discussion here.

ManVhv 01:02, 6 June 2007 (UTC)

I am usually a proponent of the "two-article" model you mention above: one for the causative/etiologic agent and a separate one for the disease (with, in this case, a third "genus-level" entry). I'm still in that camp, but I can see some of you concerns in this particular case. I think that we should give your proposal a shot—if it turns out to solve the problem, great. If not, we can always re-evaluate and try something else. Let me know if you want any help in the reconstruction phase. -- MarcoTolo 01:49, 12 June 2007 (UTC)


[edit] Vaccine Research

>>Previous studies have determined that this vaccine is approximately 70% effective in women, but does not prevent the disease in men. [22]

I have read material about Herpevac that states that the vaccine didn't offer HSV-2 protection to people who already had HSV-1 infection. I assume this means that someone who already has HSV-1 will have the same level of immunity to HSV-2 as a completely uninfected person who is given the vaccine. HSV-1 infection is very common. If someone could find some hard information on this it would be worth updating that section.

Your assumption is incorrect, and no section update is needed. It may be worth noting that the vaccine did not work well with HSV-1 infected patients, but it is absolutely wrong to suggest any "conclusion" about what that means for the immunity of people infected with HSV-1. As a matter of fact, there is copious research which indicates that HSV-1 infection has no helpful effect w.r.t. HSV-2 infection, just as Chicken Pox (HSV-3) also has nothing to do with it. ManVhv 19:30, 15 August 2007 (UTC)

[edit] Talk prior to 5 June moved to Archive

I have moved talk prior to 5 June 2007 to this archive.

ManVhv 00:57, 6 June 2007 (UTC)

[edit] Symptoms

Could someone please add more details on symptoms of HSV 1 and 2? There isn't much discussion of what the symptoms are like. —Preceding unsigned comment added by 71.130.209.38 (talk) 22:07, August 24, 2007 (UTC)

[edit] Symptoms

Could someone please add more details on symptoms of HSV 1 and 2? There isn't much discussion of what the symptoms are like. 71.130.209.38 22:11, 24 August 2007 (UTC)


Could someone please add a section on HSV tests? Which ones are available and their accuracy? —Preceding unsigned comment added by 24.215.198.79 (talk) 01:25, 26 November 2007 (UTC)

[edit] see also?

i am wondering why does it say to see alzheimer's disease? what is the connection between the two? (Dachronic215 22:33, 7 November 2007 (UTC))

There is no connection and I have deleted it.GrahamColm(Talk ) 18:17, 25 November 2007 (UTC)

There has been speculation and some research to suggest they may be a link since before 1983 (as far back as PubMed would locate a hit - see PMID 6308942). Recent papers hinting a link are PMID 16242250 & PMID 16463223. But as an old paper (PMID 15319093) points out, association has not been proof of cause (vs effect of Alzheimer plaques perhaps encouraging HSV). Still it remains topical - see NetDoctor report Alzheimer's disease may be linked to cold sore virus from 1st Nov'07 (although PubMed does not seem to list any newly published material by Itzhaki, the lead researcher mentioned, since Jan'07). David Ruben Talk 19:20, 25 November 2007 (UTC)

[edit] HSV genome link?

In some of the external links, also on what google brings up, there are statements like 'the full genome of HSV 1/2 is known'. Any URL anyone? —Preceding unsigned comment added by 217.80.81.221 (talk) 04:51, 22 December 2007 (UTC)

[edit] "excema"

The proper spelling of the skin condition characterized by itchy, irritated, inflamed skin is "eczema" [1].

There is no word in the English language (UK English or US English) spelled "excema". I have corrected this in the main article.

I would also like to see a citation or two that eczema can cause herpes to flare up.

Networkprosource (talk) 18:07, 7 March 2008 (UTC)

[edit] Oral/Genital infection rates

The statistics only show HSV-1 and HSV-2 infection rates, not the location as to what's infected. Klosterdev (talk) 03:05, 2 April 2008 (UTC) Edit: Whoop, my bad, wrong article. Klosterdev (talk) 03:06, 2 April 2008 (UTC)