Talk:HER2/neu

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  • The following excerpt from the article seems self-contradictory: HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. However, ErbB receptors dimerise on ligand binding. Is HER2 an "adopted orphan" receptor, and if so, what is its ligand? Boghog2 19:03, 4 June 2007 (UTC)