EHNA

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EHNA
Systematic (IUPAC) name
3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride
Identifiers
CAS number	59262-86-1
ATC code	?
PubChem	359137
Chemical data
Formula	C14H24ClN5O
Mol. mass	313.826 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

EHNA (erythro-9-(2-hydroxy-3-nonyl)adenine) is a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type-2 (PDE2).^[1][2]

[edit] References

1. ^ Podzuweit T, Nennstiel P and Muller A (1995) "Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine". Cell Signal 7:733-8. PMID 8519602
2. ^ Méry PF, Pavoine C, Pecker F and Fischmeister R (1995). "Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes". Mol Pharmacol 48:121-130 PMID 7623766

v • d • e Selective Phosphodiesterase inhibitors (C01CE, G04BE) PDE1 Vinpocetine PDE2 EHNA PDE3 Amrinone, Bucladesine, Enoximone, Milrinone PDE4 Cilomilast, Etazolate, HT-0712, Ibudilast, Mesembrine, Rolipram PDE5 Avanafil, Sildenafil, Tadalafil, Udenafil, Vardenafil