Talk:Doxylamine

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The structural formula given in the diagram is false. It is missing an amine group in one of the rings.

Contents 1 Canada in the Commonwealth ? 2 Structural diagram 3 Anecdotal information 4 UNISOM 5 "Anti-allergy power" 6 Pregnancy Category 7 Side Effects

[edit] Canada in the Commonwealth ?

of course it is

  I'm not sure about that.

Well, according to http://en.wikipedia.org/wiki/Commonwealth Canada is a Commonwealth nation.

Canada is absolutely in the Commonwealth 149.135.110.235 09:29, 5 December 2006 (UTC)

i'm sorry but med "Doxylamine" shinked my panis, has anyone exprience this effect. —Preceding unsigned comment added by 24.19.146.63 (talk) 15:13, 31 January 2008 (UTC)

[edit] Structural diagram

Im not at all experienced at Wiki editting, so il ask if somebody else can find a correct structural diagram that includes all the amine groups. 220.233.195.181 12:30, 26 June 2006 (UTC)

I need information about the legal status of this substance in Australia.

It is an 'over the counter' drug in Australia. I bought some about 3 hours ago in Sydney :) Marked "PHARMACIST ONLY MEDICINE". 149.135.110.235 09:31, 5 December 2006 (UTC)

[edit] Anecdotal information

I'm an insomniac, and I've tried this medicine as a sleep aid. I weigh 56 kg (124 lb). It comes in tablets containing 25 mg. Try half a tablet. A whole tablet makes it very hard to get up the next day. Also, don't take two tablets at once. It made my skin and muscles hypersensitive, so that my blanket and mattress felt itchy, and it made my eyes and nose feel very dry (as one might expect from an antihistamine). Also, chasing half a tablet with a glass of wine is very effective as a "sleeping potion" of sorts. I hope this helps. Also, I don't find the article confusing, so I'm removing the tag. Peace be upon you. 24.95.48.112 09:54, 7 January 2007 (UTC)

[edit] UNISOM

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This is the brand name used in the USA, I do not see this mentioned. Maybe that would imply commercial endorsement, but the brand names in other countries is shown. —The preceding unsigned comment was added by Jokem (talk • contribs) 21:45, 25 April 2007 (UTC).

[edit] "Anti-allergy power"

"...has anti-allergy power superior to almost every other antihistamine on the market, with the exception of diphenhydramine"
Frankly, this a very vague and unsourced information; also, the formulation isn't too fortunate. First, how can one quantify the antiallergic effect? Second, it seems more a personal impression than a factual information to me, and if it comes to personal impressions, clemastine, ketotifen, hydroxizine and cetirizine are the "non plus ultras" of antiallergics in my opinion. It would be great to back up the opinion given in article with some factual and objective data/source.--84.163.87.66 10:40, 28 April 2007 (UTC)

I agree that this statement needs a source, but of course it's possible to study efficacy of antihistamines vs. one another. A study would just have two groups (or more likely three, one being placebo), taking two different antihistamines, and see what percentage of each group's symptoms are alleviated. So it's kind of just a "personal impression" averaged out over a large group of people. Diphenhydramine is generally considered the gold standard for antihistamines.

On the other hand it may be silly to make a statement in the article as if there were a definite hierarchy. Different studies sometimes show different results, so sourcing is definitely necessary. --Galaxiaad 16:31, 16 October 2007 (UTC)

[edit] Pregnancy Category

According to the Wikipedia page on pregnancy categories (which appears to agree with the FDA):

Category A: Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Please cite an authoritative source before calling this category A, or adequate and well-controlled studies at least. I have reason to suspect this is actually category B. Epylar 05:34, 30 April 2007 (UTC)

Does anyone know up to how many times it can be used with vitamin B6 for hyperemisis?? I am dying and am very desperate to carry to full term. I am ready to ake a shameful decision to abort due to the inability to function!!

[edit] Side Effects

The phrase "Other drugs with well known anticholinergic effects include many antipsychotic and tricyclic antidepressant drugs" should be removed. What does this have to do with Doxylamine? It is not an antipsychotic or antidepressant. And there are hundreds of drugs with anticholinergic effects, most of which are not antipsychotic or antidepressant.