Diclofenamide

From Wikipedia, the free encyclopedia

Diclofenamide
Systematic (IUPAC) name
4,5-dichlorobenzene-1,3-disulfonamide
Identifiers
CAS number	120-97-8
ATC code	S01EC02
PubChem	3038
DrugBank	APRD00131
Chemical data
Formula	C6H6Cl2N2O4S2
Mol. mass	305.16 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	55%
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Diclofenamide (or dichlorphenamide) is a sulfonamide and a carbonic anhydrase inhibitor.

[edit] References

• Tawil R, McDermott M, Brown R, Shapiro B, Ptacek L, McManis P, Dalakas M, Spector S, Mendell J, Hahn A, Griggs R (2000). "Randomized trials of dichlorphenamide in the periodic paralyses. Working Group on Periodic Paralysis.". Ann Neurol 47 (1): 46–53. PMID 10632100. 
• Okada S, Izumi W, Murai M, Komatsu H, Ishimitsu S (1991). "[Diclofenamide Reference Standard (Control 891) of National Institute of Hygienic Sciences]". Eisei Shikenjo Hokoku 109: 148–50. PMID 1364383. 

v • d • e Ophthalmologicals: antiglaucoma preparations and miotics (S01E) Sympathomimetics Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine Parasympathomimetics Aceclidine • Acetylcholine • Carbachol • Demecarium • Echothiophate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon • Pilocarpine Carbonic anhydrase inhibitors Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide Beta blocking agents Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol Prostaglandin analogues Bimatoprost • Latanoprost • Travoprost • Unoprostone Other agents Dapiprazole • Guanethidine