Carteolol

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Carteolol
Systematic (IUPAC) name
5-[2-hydroxy-3- (tert-butylamino) propoxy]- 3,4-dihydro-1H-quinolin-2-one
Identifiers
CAS number	51781-06-7
ATC code	C07AA15 S01ED05
PubChem	2583
DrugBank	APRD00195
Chemical data
Formula	C16H24N2O3
Mol. mass	292.373 g/mol
Pharmacokinetic data
Bioavailability	85%
Metabolism	hepatic, active with 8-hyrdocarteolol
Half life	6-8 hours
Excretion	Renal (50-70%)
Therapeutic considerations
Pregnancy cat.	C(US)
Legal status
Routes	oral

Carteolol is a beta blocking agent

[edit] External links

• El-Kamel A, Al-Dosari H, Al-Jenoobi F. "Environmentally responsive ophthalmic gel formulation of carteolol hydrochloride.". Drug Deliv 13 (1): 55–9. doi:10.1080/10717540500309073. PMID 16401594. 
• Kuwahara K, Oizumi N, Fujisawa S, Tanito M, Ohira A (2005). "Carteolol hydrochloride protects human corneal epithelial cells from UVB-induced damage in vitro.". Cornea 24 (2): 213–20. doi:10.1097/01.ico.0000141232.41343.9d. PMID 15725891. 
• Trinquand C, Romanet J, Nordmann J, Allaire C (2003). "[Efficacy and safety of long-acting carteolol 1% once daily. A double-masked, randomized study]". J Fr Ophtalmol 26 (2): 131–6. PMID 12660585. 

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