DAN (protein)

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neuroblastoma, suppression of tumorigenicity 1
Identifiers
Symbol	NBL1
Alt. Symbols	DAN
Entrez	4681
HUGO	7650
OMIM	600613
RefSeq	NM_182744
UniProt	P41271
Other data
Locus	Chr. 1 p36.3-36.2

DAN is a protein that binds the 5' cap of mRNA and begins degradation in the 3' to 5' direction.

DAN is in direct competition with the Poly-A binding proteins (PABP), which leads to either translation or degradation.

[edit] External links

• MeSH DAN+protein,+human+(Neuroblastoma)

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