Currarino syndrome

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Currarino syndrome Classification and external resources
OMIM	176450
DiseasesDB	33509

Currarino syndrome is a condition where the sacrum (the fused vertebrae forming the back of the pelvis) is not formed properly, there is a mass in the presacral space in front of sacrum, and there are malformations of the anus or rectum. The condition is an autosomal dominant genetic trait caused by a mutation in the HLXB9 homeobox gene.

Currarino syndrome may cause an anterior meningocele or presacral teratoma, or both.

v • d • e Congenital malformations and deformations of nervous system (Q00-Q07, 740-742) Brain Anencephaly (Acephaly, Acrania, Iniencephaly) - Encephalocele - Microcephaly - Congenital hydrocephalus (Dandy-Walker syndrome) - other reduction deformities (Holoprosencephaly, Lissencephaly, Pachygyria, Hydranencephaly) - Septo-optic dysplasia - Megalencephaly - Congenital cerebral cysts (Porencephaly, Schizencephaly) - Congenital brain tumors Brain stem Arnold-Chiari malformation Spinal cord Spina bifida - Currarino syndrome - Sacrococcygeal teratoma - Diastematomyelia - Syringomyelia see also non-congenital CNS and PNS (G, 320-359)

v • d • e Bones of torso Sternum Suprasternal notch, Manubrium, Sternal angle, Body of sternum, Xiphisternal joint, Xiphoid process Rib specific ribs (1, 2, 9, 10, 11, 12, false - 8-12, floating - 11-12) - parts (Angle, Tubercle, Costal groove, Neck, Head) General vertebral structures body of vertebra, vertebral arch (pedicle, lamina, vertebral notch), foramina (vertebral, intervertebral), processes (transverse, articular / zygapophysis, spinous) Cervical vertebrae C1 (anterior arch, posterior arch, lateral mass), C2 (dens), C3, C4, C5, C6, C7 anterior tubercle, posterior tubercle, foramen transversarium Thoracic vertebrae T1, T2, T3, T4, T5, T6, T7, T8, T9, T10, T11, T12 costal facets (superior, inferior, transverse) Lumbar vertebrae accessory process, mammillary process, L5 Sacrum pelvic surface (anterior sacral foramina), dorsal surface (posterior sacral foramina, median sacral crest, medial sacral crest, lateral sacral crest), lateral surface (sacral tuberosity), base, sacral hiatus - presacral space - sacral promontory - sacral canal - ala of sacrum - sacrovertebral angle