Corydaline synthase

From Wikipedia, the free encyclopedia

In enzymology, a corydaline synthase (EC 2.1.1.147) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + palmatine + 2 NADPH + H⁺ S-adenosyl-L-homocysteine + corydaline + 2 NADP⁺

The 4 substrates of this enzyme are S-adenosyl methionine, palmatine, NADPH, and H⁺, whereas its 3 products are S-adenosylhomocysteine, corydaline, and NADP⁺.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase.

[edit] References

• IUBMB entry for 2.1.1.147
• BRENDA references for 2.1.1.147 (Recommended.)
• PubMed references for 2.1.1.147
• PubMed Central references for 2.1.1.147
• Google Scholar references for 2.1.1.147
• Rueffer M, Bauer W and Zenk MH (1994). "The formation of corydaline and related alkaloids in Corydalis cava in vivo and in vitro". Canad. J. Chem. 72: 170–175. 

[edit] External links

The CAS registry number for this enzyme class is 155807-67-3.

• IUBMB entry for 2.1.1.147

• KEGG entry for 2.1.1.147

• BRENDA entry for 2.1.1.147

• NiceZyme view of 2.1.1.147

• EC2PDB: PDB structures for 2.1.1.147

• PRIAM entry for 2.1.1.147

• PUMA2 entry for 2.1.1.147

• IntEnz: Integrated Enzyme entry for 2.1.1.147

• MetaCyc entry for 2.1.1.147

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050631: corydaline synthase

• AMIGO entry for GO code 0050631: corydaline synthase