Talk:CHOP
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this article separately describes the H in CHOP as being 'Hydroxyrubicin' and then 'hydroxydoxorubicin'. Which is it?
One one hand, this abstract: http://www3.interscience.wiley.com/cgi-bin/abstract/112706492/ABSTRACT?CRETRY=1&SRETRY=0
says, "Hydroxyrubicin is a synthetic analog of doxorubicin in which the basic amino group at the C-3 has been replaced by a hydroxyl group...". So they are not the same.
Yet this page: http://ctd.mdibl.org/detail.go;jsessionid=92F12340E7F4A23A86B9242140E2E2AE?type=chem&acc=C042907 says that hydroxyrubicin is indeed a synonym for doxorubicin. "Chemical Synonyms 3'-deamino-4'-epi-3'-hydroxydoxorubin; 3-DHD; hydroxyrubicin"
Kenmcl2 04:57, 3 July 2007 (UTC)
According to PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=72398 hydroxydoxorubicin and hydroxyrubicin are same compound that is not doxorubicin but 3'-Deamino-3'-hydroxydoxorubicin where amino group has been replaced by a hydroxyl group. —Preceding unsigned comment added by Tanevala (talk • contribs) 17:18, 18 September 2007 (UTC)
H must come from Hydroxydaunorubicin which is a synonym for doxorubicin.
[edit] HIV
CHOP for DLBCL in HIV seems fairly safe doi:10.1111/j.1365-2141.2007.06943.x JFW | T@lk 09:59, 24 January 2008 (UTC)
