Chakragati mouse

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Chakragati mouse (ckr) is an insertional transgenic mouse mutant displaying hyperactive behaviour and circling. It is also deficient in prepulse inhibition, latent inhibition and has brain abnormalities that are typical to endophenotypic models of schizophrenia, which make it useful in screening for antipsychotic drug candidates.[1] The mouse is currently licensed by Chakra Biotech.

[edit] References

  1. ^ Dawe GS, Ratty AK (2007). "The chakragati mouse: A mouse model for rapid in vivo screening of antipsychotic drug candidates". doi:10.1002/biot.200700145. PMID 17886239. 


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