Talk:Burkitt's lymphoma

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In Harrison's Principles of Internal Medicine, 16th edition, chapter 97, it says that Burkitt's lymphoma "is the most rapidly progressive human tumor". However, elsewhere I read that about ovarian Endodermal sinus tumor, previously known as Yolk sac tumor. Does anyone know anything about it? Ehudzel 22:55, 9 February 2007 (UTC) you suck —Preceding unsigned comment added by 64.8.149.194 (talk) 15:26, 16 October 2007 (UTC)

I had Burkitt's lymphoma as a 6-year old back in the mid-1980's and at that time there was very little pediatric protocol... I was like a guinea pig for treatment, but one thing the doctors knew for sure was that it had to be attacked quickly and throughly b/c this lymphoma was known industry wide to be capable of doubling its size in less than 24 hours. Hence, I underwent chemotherapy, radiation, and over 12 hours of surgery. —Preceding unsigned comment added by 216.201.151.10 (talk) 21:02, 18 February 2008 (UTC)

The article states that "Normal B cells possess rearranged immunoglobulin heavy (IgH) and light chain genes, unlike most T-cells and other cells of the body in which the genes are germline". This is true in so far as only B cells have distinct Immunoglobin Heavy and Light Chains. However, T cells DO undergo gene rearrangement to produce unique T-cell Receptors using the same mechanisms as found in B cells. Like B cells they start their development with a germline DNA canvas and both sets of cells will mature into lymphocytes with unique receptors structurally suited to their role in antigen-binding. Allasse Lossehelin 15.03.08