Biphenyl synthase

From Wikipedia, the free encyclopedia

In enzymology, a biphenyl synthase (EC 2.3.1.177) is an enzyme that catalyzes the chemical reaction

3 malonyl-CoA + benzoyl-CoA 4 CoA + 3,5-dihydroxybiphenyl + 4 CO₂

Thus, the two substrates of this enzyme are malonyl-CoA and benzoyl-CoA, whereas its 3 products are CoA, 3,5-dihydroxybiphenyl, and CO₂.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:benzoyl-CoA malonyltransferase. This enzyme is also called BIS.

[edit] References

• IUBMB entry for 2.3.1.177
• BRENDA references for 2.3.1.177 (Recommended.)
• PubMed references for 2.3.1.177
• PubMed Central references for 2.3.1.177
• Google Scholar references for 2.3.1.177
• Liu B, Beuerle T, Klundt T, Beerhues L (2004). "Biphenyl synthase from yeast-extract-treated cell cultures of Sorbus aucuparia". Planta. 218: 492–6. doi:10.1007/s00425-003-1144-y. PMID 14595561. 

[edit] External links

• IUBMB entry for 2.3.1.177

• KEGG entry for 2.3.1.177

• BRENDA entry for 2.3.1.177

• NiceZyme view of 2.3.1.177

• EC2PDB: PDB structures for 2.3.1.177

• PRIAM entry for 2.3.1.177

• PUMA2 entry for 2.3.1.177

• IntEnz: Integrated Enzyme entry for 2.3.1.177

• MetaCyc entry for 2.3.1.177

• Atomic-resolution structures of enzymes belonging to this class