Biliverdin reductase

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biliverdin reductase A
Identifiers
Symbol	BLVRA
Alt. Symbols	BLVR
Entrez	644
HUGO	1062
OMIM	109750
RefSeq	NM_000712
UniProt	P53004
Other data
EC number	1.3.1.24
Locus	Chr. 7 p14-cen

biliverdin reductase B
Identifiers
Symbol	BLVRB
Alt. Symbols	FLR
Entrez	645
HUGO	1063
OMIM	600941
RefSeq	NM_000713
UniProt	P30043
Other data
EC number	1.3.1.24
Locus	Chr. 19 q13.1-13.2

Biliverdin reductase is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond.

biliverdin

bilirubin

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• MeSH biliverdin+reductase

v • d • e Oxidoreductases: CH-CH oxidoreductases (EC 1.3) 1.3.1. NAD/NADP acceptor Enoyl-acyl carrier protein reductase/Enoyl ACP reductase - 7-Dehydrocholesterol reductase - Biliverdin reductase - 2,4 Dienoyl-CoA reductase 1.3.3. Oxygen acceptor Dihydroorotate dehydrogenase - Coproporphyrinogen III oxidase - Protoporphyrinogen oxidase - 1.3.5. Quinone Succinate dehydrogenase 1.3.99. Other acceptors Fumarate reductase - Butyryl CoA dehydrogenase - Acyl CoA dehydrogenase - 5-alpha reductase - Glutaryl-CoA dehydrogenase - Isovaleryl coenzyme A dehydrogenase

v • d • e Metabolism: amino acid metabolism - porphyrin enzymes Porphyrin biosynthesis initial mitochondrial: Aminolevulinic acid synthase - Porphobilinogen synthase cytosolic: Porphobilinogen deaminase - Uroporphyrinogen III synthase - Uroporphyrinogen III decarboxylase - Coproporphyrinogen III oxidase terminal mitochondrial: Protoporphyrinogen oxidase - Ferrochelatase Heme breakdown to bile spleen: Heme oxygenase - Biliverdin reductase liver: UDP-glucuronosyltransferase see also disorders, intermediates