Beta-glucosidase

From Wikipedia, the free encyclopedia

Identifiers
Symbol GBA
Alt. Symbols GLUC
Entrez 2629
HUGO 4177
OMIM 606463
RefSeq NM_000157
UniProt P04062
Other data
EC number 3.2.1.21
Locus Chr. 1 q22
glucosidase, beta, acid 3 (cytosolic)
Identifiers
Symbol GBA3
Entrez 57733
HUGO 19069
OMIM 606619
RefSeq NM_020973
UniProt Q9H227
Other data
EC number 3.2.1.21
Locus Chr. 4 p15.31

Beta-glucosidase is a glucosidase enzyme which acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (ie, the disacharide 'cellobiose').

Cellulose is largely composed of polymers of beta-bond linked glucose molecules, and beta-glucosidases are required by organisms (some fungi, bacteria, termites) that can consume it.

Lysozyme, an enzyme secreted in tears to prevent bacterial infection of the eye, is also a beta-glucosidase that cleaves β1->4 bonds between N-acetylglucosamine and N-acetylmuramic acid sugars within the peptidoglycan cell walls of gram-negative bacteria.

[edit] External links

[edit] References

Languages