Talk:Ascites

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[edit] Historical Correlate

I particularly enjoy the statement "Comparable is also Numeri 5:11ff, where a confirmed adulteress is punished with swelling of the abdomen."

Might they be referring to pregnancy?

12.210.82.110 22:14, 21 March 2007 (UTC) bwhitehurst81


[edit] Methods

Is it worth mentioning that, in the past, one of the methods of propagating tissue culture cells was to propagate them in the peritoneum of syngeneic mice, and that this caused ascites formation? They even used to generate antibodies by injecting mice with monoclonal B-cells.... user:Fhayashi

I'm not sure... it sounds like a footnote in the annals of science, IMHO. JFW | T@lk 20:43, 12 July 2005 (UTC)
The tissue culture method might be, but as a method of making antibodies from hybridomas, it's definitely not - it's still very widely used. In fact, i believe it's the standard way of making monoclonal antibodies, as it's easy, cheap, gives very high concentrations, and doesn't need much purification afterwards, none of which are true of growing hybridomas in culture. Certainly, plenty of the antibodies in my lab's freezer are ascites fluid. I think this method is now banned in the EU on animal welfare grounds, but it's still done in the US. -- Tom Anderson 3/1/2008 2159 +0000 —Preceding unsigned comment added by 128.40.81.216 (talk) 21:59, 3 January 2008 (UTC)

[edit] BSG guidelines

Prof Moore and Dr Aithal have written a guideline for the management of cirrhotic ascites. May be worth using for the paragraphs on management[1]. JFW | T@lk 15:28, 12 September 2006 (UTC)

It's a very comprehensive guideline. I'll see if I can work it into this article. JFW | T@lk 22:53, 3 October 2006 (UTC)

[edit] B-cells

It's correct, even B-cells could be cultured in this ascitic areas to accomplish monoclonal antibody production. Ascites also exist in human cancers, like pancreatic cancer.

B cells? You mean beta cells? Or do you suggest cytology is sent? The article already mentions cancer. JFW | T@lk 22:53, 3 October 2006 (UTC)

[edit] Not mineralocorticoid

doi:10.1002/hep.21699 - the role of the RAS system may be overvalued. JFW | T@lk 16:39, 27 June 2007 (UTC)