Talk:Antiphospholipid syndrome
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The suggestion is made in this article that the anti phospholipid syndrome is caused by auto antibodies directed against negatively charged phospholipids on the cell/platelet surface. However for almost 15 years it is known that most of the antibodies in this syndrome are directed against proteins that bind negatively charged phospholipids such as prothrombin and beta-2-glycoprotein-1. It is the binding of antibodies to coagulation proteins that causes altered coagulation processes not the binding of antibodies against negatively charged phospholipids.
I suggest to change the article to correct this misunderstanding. Bio2mancer 24 june 2006.
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[edit] Sapporo criteria
We should mention the Sapporo criteria: PMID 10403256 . JFW | T@lk 20:58, 4 July 2006 (UTC)
- And a recent amendment: PMID 16420554 . JFW | T@lk 20:59, 4 July 2006 (UTC)
[edit] Recent review
A recent systematic review on the treatment shows how little we actually know about optimal treatment for this: PMID 16507806. JFW | T@lk 21:01, 4 July 2006 (UTC)
[edit] Page has massive changes
Since 07 NOV 06...actually making this page very inaccurate. Please revert back to previous revision before 07 NOV 06. Tried to get the categories back in. Hopefully I did it right.eyz 00:10, 21 November 2006 (UTC)
[edit] Typo
Changed a typo (phosphotidylserine to Phosphatidylserine). Rage italic 15:54, 30 March 2007 (UTC)
[edit] APSFA Page
Actaully that page is cited and is HONCode certifed. Very few sites can say that. It has a bio. upon request.eyz 17:53, 20 May 2007 (UTC)
[edit] APSCORE
APSCORE is no longer functioning due to lack of funding from the CDC and NIH. Link Removed. eyz
[edit] Nature of antibodies
Some antibodies are more aborto/thrombogenic than others PMID 17440049 JFW | T@lk 06:42, 7 August 2007 (UTC)
