Alkylmercury lyase

From Wikipedia, the free encyclopedia

In enzymology, an alkylmercury lyase (EC 4.99.1.2) is an enzyme that catalyzes the chemical reaction

an alkylmercury + H⁺ an alkane + Hg₂+

Thus, the two substrates of this enzyme are alkylmercury and H⁺, whereas its two products are alkane and Hg2+.

This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that do not fit into any other sub-class. The systematic name of this enzyme class is alkylmercury mercuric-lyase (alkane-forming). Other names in common use include organomercury lyase, organomercurial lyase, and alkylmercury mercuric-lyase.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1S6L.

[edit] References

• IUBMB entry for 4.99.1.2
• BRENDA references for 4.99.1.2 (Recommended.)
• PubMed references for 4.99.1.2
• PubMed Central references for 4.99.1.2
• Google Scholar references for 4.99.1.2
• Tezuka T, Tonomura K (Tokyo). "Purification and properties of an enzyme catalyzing the splitting of carbon-mercury linkages from mercury-resistant Pseudomonas K-62 strain. I. Splitting enzyme 1". J. Biochem.: 79–87. PMID 9382. 

[edit] External links

The CAS registry number for this enzyme class is 72560-99-7.

• IUBMB entry for 4.99.1.2

• KEGG entry for 4.99.1.2

• BRENDA entry for 4.99.1.2

• NiceZyme view of 4.99.1.2

• EC2PDB: PDB structures for 4.99.1.2

• PRIAM entry for 4.99.1.2

• PUMA2 entry for 4.99.1.2

• IntEnz: Integrated Enzyme entry for 4.99.1.2

• MetaCyc entry for 4.99.1.2

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018836: alkylmercury lyase

• AMIGO entry for GO code 0018836: alkylmercury lyase