Alginate synthase

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In enzymology, an alginate synthase (EC 2.4.1.33) is an enzyme that catalyzes the chemical reaction

GDP-D-mannuronate + (alginate)n GDP + (alginate)n⁺1

Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP and (alginate)n+1.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. This enzyme is also called mannuronosyl transferase. This enzyme participates in fructose and mannose metabolism.

[edit] References

• IUBMB entry for 2.4.1.33
• BRENDA references for 2.4.1.33 (Recommended.)
• PubMed references for 2.4.1.33
• PubMed Central references for 2.4.1.33
• Google Scholar references for 2.4.1.33
• Lin TY, Hassid WZ (1966). "Pathway of algnic acid synthesis in the marine brown alga, Fucus gardneri Silva". J. Biol. Chem. 241: 5284–97. PMID 5954796. 

[edit] External links

The CAS registry number for this enzyme class is 37257-31-1.

• IUBMB entry for 2.4.1.33

• KEGG entry for 2.4.1.33

• BRENDA entry for 2.4.1.33

• NiceZyme view of 2.4.1.33

• EC2PDB: PDB structures for 2.4.1.33

• PRIAM entry for 2.4.1.33

• PUMA2 entry for 2.4.1.33

• IntEnz: Integrated Enzyme entry for 2.4.1.33

• MetaCyc entry for 2.4.1.33

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047643: alginate synthase

• AMIGO entry for GO code 0047643: alginate synthase