Talk:Acute promyelocytic leukemia

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I made some major edits. Any comments?

Well, I know that autologous bone marrow transplants work as treatment in a relapse of this disorder, since that's what they did with my mom when she was ill with APL. Dunno if they still use autogenic as well.


another viewpoint-------------------

Autologous bone marrow "transplant" or autologous stem cell infusions do not cure anything, except manage the side-effects of the "real" treatments. The treatment is whatever method is used to kill the malignant process in the bone marrow or elsewhere. The autologous stem cells are simply a way of decreasing the time for restoration of normal bone marrow production of white cells, red cells and platelets. They are basically a fancy blood transfusion. If there is no benefit from the chemotherapy or radiation (as is so far the case in high-risk breast cancer) then the autologous stems cells merely restore a person to the state they were in before the "real" treatment killed their marrow.

APML is often very effectively retreated in relapse, unlike many other myelocytic leukemias.

[edit] Anniversary review

http://bloodjournal.hematologylibrary.org/cgi/content/abstract/111/5/2505 - historical review of APL. JFW | T@lk 09:50, 26 February 2008 (UTC)