3-methyleneoxindole reductase

From Wikipedia, the free encyclopedia

In enzymology, a 3-methyleneoxindole reductase (EC 1.3.1.17) is an enzyme that catalyzes the chemical reaction

3-methyl-1,3-dihydroindol-2-one + NADP⁺ 3-methylene-1,3-dihydro-2H-indol-2-one + NADPH + H⁺

Thus, the two substrates of this enzyme are 3-methyl-1,3-dihydroindol-2-one and NADP⁺, whereas its 3 products are 3-methylene-1,3-dihydro-2H-indol-2-one, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase. This enzyme is also called 3-methyloxindole:NADP+ oxidoreductase.

[edit] References

• IUBMB entry for 1.3.1.17
• BRENDA references for 1.3.1.17 (Recommended.)
• PubMed references for 1.3.1.17
• PubMed Central references for 1.3.1.17
• Google Scholar references for 1.3.1.17
• Moyed HS, Williamson V (1967). "Multiple 3-methyleneoxindole reductases of peas, differential inhibition by synthetic auxins". J. Biol. Chem. 242: 1075–7. PMID 6021071. 

[edit] External links

The CAS registry number for this enzyme class is 37255-29-1.

• IUBMB entry for 1.3.1.17

• KEGG entry for 1.3.1.17

• BRENDA entry for 1.3.1.17

• NiceZyme view of 1.3.1.17

• EC2PDB: PDB structures for 1.3.1.17

• PRIAM entry for 1.3.1.17

• PUMA2 entry for 1.3.1.17

• IntEnz: Integrated Enzyme entry for 1.3.1.17

• MetaCyc entry for 1.3.1.17

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047567: 3-methyleneoxindole reductase

• AMIGO entry for GO code 0047567: 3-methyleneoxindole reductase