3-hydroxybenzyl-alcohol dehydrogenase

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In enzymology, a 3-hydroxybenzyl-alcohol dehydrogenase (EC 1.1.1.97) is an enzyme that catalyzes the chemical reaction

3-hydroxybenzyl alcohol + NADP⁺ 3-hydroxybenzaldehyde + NADPH + H⁺

Thus, the two substrates of this enzyme are 3-hydroxybenzyl alcohol and NADP⁺, whereas its 3 products are 3-hydroxybenzaldehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-hydroxybenzyl-alcohol:NADP+ oxidoreductase. Other names in common use include m-hydroxybenzyl alcohol dehydrogenase, m-hydroxybenzyl alcohol (NADP+) dehydrogenase, and m-hydroxybenzylalcohol dehydrogenase. This enzyme participates in toluene and xylene degradation.

[edit] References

• IUBMB entry for 1.1.1.97
• BRENDA references for 1.1.1.97 (Recommended.)
• PubMed references for 1.1.1.97
• PubMed Central references for 1.1.1.97
• Google Scholar references for 1.1.1.97
• Forrester PI, Gaucher GM (1972). "m-Hydroxybenzyl alcohol dehydrogenase from Penicillium urticae". Biochemistry. 11: 1108–14. doi:10.1021/bi00756a026. PMID 4335290. 

[edit] External links

The CAS registry number for this enzyme class is 9075-73-4.

• IUBMB entry for 1.1.1.97

• KEGG entry for 1.1.1.97

• BRENDA entry for 1.1.1.97

• NiceZyme view of 1.1.1.97

• EC2PDB: PDB structures for 1.1.1.97

• PRIAM entry for 1.1.1.97

• PUMA2 entry for 1.1.1.97

• IntEnz: Integrated Enzyme entry for 1.1.1.97

• MetaCyc entry for 1.1.1.97

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047048: 3-hydroxybenzyl-alcohol dehydrogenase

• AMIGO entry for GO code 0047048: 3-hydroxybenzyl-alcohol dehydrogenase