2'-hydroxydaidzein reductase

From Wikipedia, the free encyclopedia

In enzymology, a 2'-hydroxydaidzein reductase (EC 1.3.1.51) is an enzyme that catalyzes the chemical reaction

2'-hydroxy-2,3-dihydrodaidzein + NADP⁺ 2'-hydroxydaidzein + NADPH + H⁺

Thus, the two substrates of this enzyme are 2'-hydroxy-2,3-dihydrodaidzein and NADP⁺, whereas its 3 products are 2'-hydroxydaidzein, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase. Other names in common use include NADPH:2'-hydroxydaidzein oxidoreductase, HDR, and 2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase. This enzyme participates in isoflavonoid biosynthesis.

[edit] References

• IUBMB entry for 1.3.1.51
• BRENDA references for 1.3.1.51 (Recommended.)
• PubMed references for 1.3.1.51
• PubMed Central references for 1.3.1.51
• Google Scholar references for 1.3.1.51
• Fischer D, Ebenau-Jehle C, Grisebach H (1990). "Phytoalexin synthesis in soybean: purification and characterization of NADPH:2'-hydroxydaidzein oxidoreductase from elicitor-challenged soybean cell cultures". Arch. Biochem. Biophys. 276: 390–5. doi:10.1016/0003-9861(90)90737-J. PMID 2306102. 

[edit] External links

The CAS registry number for this enzyme class is 126125-01-7.

• IUBMB entry for 1.3.1.51

• KEGG entry for 1.3.1.51

• BRENDA entry for 1.3.1.51

• NiceZyme view of 1.3.1.51

• EC2PDB: PDB structures for 1.3.1.51

• PRIAM entry for 1.3.1.51

• PUMA2 entry for 1.3.1.51

• IntEnz: Integrated Enzyme entry for 1.3.1.51

• MetaCyc entry for 1.3.1.51

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047525: 2'-hydroxydaidzein reductase

• AMIGO entry for GO code 0047525: 2'-hydroxydaidzein reductase