2-hydroxy-1,4-benzoquinone reductase

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In enzymology, a 2-hydroxy-1,4-benzoquinone reductase (EC 1.6.5.7) is an enzyme that catalyzes the chemical reaction

2-hydroxy-1,4-benzoquinone + NADH + H⁺ 1,2,4-trihydroxybenzene + NAD⁺

The 3 substrates of this enzyme are 2-hydroxy-1,4-benzoquinone, NADH, and H⁺, whereas its two products are 1,2,4-trihydroxybenzene and NAD⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a quinone or similar compound as acceptor. The systematic name of this enzyme class is 2-hydroxy-1,4-benzoquinone:NADH oxidoreductase. Other names in common use include hydroxybenzoquinone reductase, 1,2,4-trihydroxybenzene:NAD oxidoreductase, and NADH:2-hydroxy-1,4-benzoquinone oxidoreductase. This enzyme participates in gamma-hexachlorocyclohexane degradation and 1,4-dichlorobenzene degradation.

[edit] References

• IUBMB entry for 1.6.5.7
• BRENDA references for 1.6.5.7 (Recommended.)
• PubMed references for 1.6.5.7
• PubMed Central references for 1.6.5.7
• Google Scholar references for 1.6.5.7
• Chakrabarty AM (1998). "Novel pathway for conversion of chlorohydroxyquinol to maleylacetate in Burkholderia cepacia AC1100". J. Bacteriol. 180: 4667–75. PMID 9721310. 

[edit] External links

• IUBMB entry for 1.6.5.7

• KEGG entry for 1.6.5.7

• BRENDA entry for 1.6.5.7

• NiceZyme view of 1.6.5.7

• EC2PDB: PDB structures for 1.6.5.7

• PRIAM entry for 1.6.5.7

• PUMA2 entry for 1.6.5.7

• IntEnz: Integrated Enzyme entry for 1.6.5.7

• MetaCyc entry for 1.6.5.7

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050625: 2-hydroxy-1,4-benzoquinone reductase

• AMIGO entry for GO code 0050625: 2-hydroxy-1,4-benzoquinone reductase