(S)-2-hydroxy-fatty-acid dehydrogenase
From Wikipedia, the free encyclopedia
In enzymology, a (S)-2-hydroxy-fatty-acid dehydrogenase (EC 1.1.1.99) is an enzyme that catalyzes the chemical reaction
- (S)-2-hydroxystearate + NAD+
2-oxostearate + NADH + H+
Thus, the two substrates of this enzyme are (S)-2-hydroxystearate and NAD+, whereas its 3 products are 2-oxostearate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-2-hydroxystearate:NAD+ oxidoreductase. Other names in common use include dehydrogenase, L-2-hydroxy fatty acid, L-2-hydroxy fatty acid dehydrogenase, and 2-hydroxy fatty acid oxidase.
[edit] References
- IUBMB entry for 1.1.1.99
- BRENDA references for 1.1.1.99 (Recommended.)
- PubMed references for 1.1.1.99
- PubMed Central references for 1.1.1.99
- Google Scholar references for 1.1.1.99
- Huang WY, Tang J (1970). "Carboxyl-terminal sequence of human gastricsin and pepsin". J. Biol. Chem. 245: 2189–93. PMID 4909888.
[edit] External links
-
- The CAS registry number for this enzyme class is 37250-33-2.

