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| ykkC-yxkD leader |
 |
| Type: |
Cis-reg; |
| 2° structure: |
Predicted; Barrick JE, Breaker RR |
| Seed alignment: |
Barrick JE, Breaker RR |
| Avg length: |
106.5 nucleotides |
| Avg identity: |
62% |
|
The YkkC/YxkD leader is a conserved RNA structure found upstream of the ykkC and yxkD genes in Bacillus subtilis and related genes in other bacteria. The function of this family is unclear although it has been suggested that it may function to switch on efflux pumps and detoxification systems in response to harmful environmental molecules.[1] The Thermoanaerobacter tengcongensis sequence AE013027 overlaps with that of purine riboswitch suggesting that the two riboswitches may work in conjunction to regulate the the upstream gene which codes for TTE0584 (Q8RC62), a member of the permease family.
[edit] References
- ^ Barrick, JE; Corbino KA, Winkler WC, Nahvi A, Mandal M, Collins J, Lee M, Roth A, Sudarsan N, Jona I, Wickiser JK, Breaker RR (2004). "New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control". Proc Natl Acad Sci U S A 101: 6421–6426. doi:10.1073/pnas.0308014101. PMID 15096624.
[edit] External links
