Wisconsin Highway 45
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| State Trunk Highway 45 |
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| Formed: | 1918-1934 | ||||||||||||
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State Trunk Highway 45 (often called Highway 45, STH 45 or WIS 45) was a number assigned to two different state highways in the U.S. state of Wisconsin:
- Highway 45 from 1917 to 1923, along the current route of U.S. Highway 63 from Red Wing, Minnesota to Ellsworth, WIS 65 and WIS 35 up to Hudson
- Highway 45 from 1923 to 1934, currently routed as Highway 34
- For the highway in Wisconsin numbered 45 since 1934, see U.S. Highway 45.

