Willem Einthoven
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| Willem Einthoven | |
Willem Einthoven in 1906
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| Born | May 21, 1860 Semarang |
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| Died | September 29, 1927 Leiden, Netherlands |
| Nationality | Dutch |
| Fields | physiologist |
| Institutions | University of Leiden |
| Alma mater | University of Utrecht |
| Known for | electrocardiogram |
| Notable awards | |
| Religious stance | Lutheran |
Willem Einthoven (Semarang, May 21, 1860 – Leiden, September 29, 1927) was a Dutch doctor and physiologist. He invented the first practical electrocardiogram (ECG or EKG) in 1903 and received the Nobel Prize in Medicine in 1924 for it.
Einthoven was born in Semarang on Java in the Dutch East Indies (now Indonesia). His father, a medical doctor, died when Einthoven was a child. His mother returned to the Netherlands with her children in 1870 and settled in Utrecht. In 1885, Einthoven received a medical degree from the University of Utrecht. He became a professor at the University of Leiden in 1886.
Before Einthoven's time, it was known that the beating of the heart produced electrical currents, but the instruments of the time could not accurately measure this phenomenon without placing electrodes directly on the heart. Beginning in 1901, Einthoven completed a series of prototypes of a string galvanometer. This device used a very thin filament of conductive wire passing between very strong electromagnets. When a current passed through the filament, the electromagnetic field would cause the string to move. A light shining on the string would cast a shadow on a moving roll of photographic paper, thus forming a continuous curve showing the movement of the string. The original machine required water cooling for the powerful electromagnets, required 5 people to operate it and weighed some 600 lb. This device increased the sensitivity of the standard galvanometer so that the electrical activity of the heart could be measured despite the insulation of flesh and bones.
Although later technological advances brought about better and more portable EKG devices, much of the terminology used in describing an EKG originated with Einthoven. His assignment of the letters P, Q, R, S and T to the various deflections is still used. The term "Einthoven's triangle" is named for him. It refers to the imaginary inverted equilateral triangle centered on the chest and the points being the standard leads on the arms and leg.
After his development of the string galvanometer, Einthoven went on to describe the electrocardiographic features of a number of cardiovascular disorders. Later in life, Einthoven turned his attention to the study of acoustics.
He died in Leiden in the Netherlands and is buried in the graveyard of the Reformed Church at 6 Haarlemmerstraatweg in Oegstgeest[1].
[edit] See also
[edit] References and further reading
- ^ Van Ditzhuijzen, Jeannette (September 9 2005). Bijna vergeten waren ze, de rustplaatsen van roemruchte voorvaderen. Trouw (Dutch newspaper), p. 9 of supplement.
- Cajavilca, Christian & Varon, Joseph (2008), “Resuscitation great. Willem Einthoven: the development of the human electrocardiogram.”, Resuscitation 76 (3): 325-8, 2008 Mar, PMID:18164799, doi:10.1016/j.resuscitation.2007.10.014, <http://www.ncbi.nlm.nih.gov/pubmed/18164799>
- Barold, S Serge (2003), “Willem Einthoven and the birth of clinical electrocardiography a hundred years ago.”, Cardiac electrophysiology review 7 (1): 99-104, 2003 Jan, PMID:12766530, <http://www.ncbi.nlm.nih.gov/pubmed/12766530>
- Schweitzer, P & Keller, S (2002), “Willem Einthoven--inventor of electrocardiography.”, Vnitrní lékarství 48 Suppl 1: 20-3, 2002 Dec, PMID:12744012, <http://www.ncbi.nlm.nih.gov/pubmed/12744012>
- Haas, L F (2001), “Willem Einthoven (1860-1927).”, J. Neurol. Neurosurg. Psychiatr. 71 (3): 407, 2001 Sep, PMID:11511722, <http://www.ncbi.nlm.nih.gov/pubmed/11511722>
- Raju, T N (1998), “The Nobel chronicles. 1924: Willem Einthoven (1860-1927).”, Lancet 352 (9139): 1560, 1998 Nov 7, PMID:9820341, <http://www.ncbi.nlm.nih.gov/pubmed/9820341>
- Davies, M K & Hollman, A (1997), “Willem Einthoven (1860-1927).”, Heart 78 (4): 324, 1997 Oct, PMID:9404240, <http://www.ncbi.nlm.nih.gov/pubmed/9404240>
- Maciel, R (1996), “[Willem Einthoven. From an arduous beginning to the Nobel Prize]”, Arq. Bras. Cardiol. 66 (4): 179-86, 1996 Apr, PMID:8935680, <http://www.ncbi.nlm.nih.gov/pubmed/8935680>
- Silverman, M E (1992), “Willem Einthoven--the father of electrocardiography.”, Clinical cardiology 15 (10): 785-7, 1992 Oct, PMID:1395193, <http://www.ncbi.nlm.nih.gov/pubmed/1395193>
- Krikler, D M & Hollman, A (1990), “The last portrait of Willem Einthoven: newly discovered links between Sir Thomas Lewis and Alexander Samojloff.”, British heart journal 64 (3): 223-6, 1990 Sep, PMID:2206718, <http://www.ncbi.nlm.nih.gov/pubmed/2206718>
- Ershler, I (1988), “Willem Einthoven--the man. The string galvanometer electrocardiograph.”, Arch. Intern. Med. 148 (2): 453-5, 1988 Feb, PMID:3277566, <http://www.ncbi.nlm.nih.gov/pubmed/3277566>
- Schwartze, D (1985), “[Willem Einthoven. Thoughts on the occasion of his 125th anniversary]”, Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete 40 (11): 356-60, 1985 Jun 1, PMID:3898619, <http://www.ncbi.nlm.nih.gov/pubmed/3898619>
- Denolin, H (1978), “Willem Einthoven. 50th commemorative anniversary.”, European journal of cardiology 8 (2): 303-4, 1978 Sep, PMID:359335, <http://www.ncbi.nlm.nih.gov/pubmed/359335>
- Tammeling, G J (1978), “Willem Einthoven as a pioneer in bronchial function.”, European journal of cardiology 8 (2): 299-302, 1978 Sep, PMID:359334, <http://www.ncbi.nlm.nih.gov/pubmed/359334>
- Snellen, H A (1978), “Willem Einthoven Memorial Symposium on Developments in Electrocardiography 1927-1977, Leiden, The Netherlands, 28 October 1977. Introduction.”, European journal of cardiology 8 (2): 201-3, 1978 Sep, PMID:359331, <http://www.ncbi.nlm.nih.gov/pubmed/359331>
- Rosol, Z (1977), “[50th anniversary of the death of Willem Einthoven (1860-1927)]”, Cas. Lek. Cesk. 116 (47): 1480, 1977 Nov 25, PMID:340042, <http://www.ncbi.nlm.nih.gov/pubmed/340042>
- Kyle, R A & Shampo, M A (1977), “Willem Einthoven.”, JAMA 237 (19): 2108, 1977 May 9, PMID:323520, <http://www.ncbi.nlm.nih.gov/pubmed/323520>
- Sulek, K (1967), “[Nobel prize in 1924 for Willem Einthoven for the discovery of the mechamism of the electrocardiogram]”, Wiad. Lek. 20 (22): 2072, 1967 Nov 15, PMID:4870668, <http://www.ncbi.nlm.nih.gov/pubmed/4870668>
- “WILLEM EINTHOVEN (1860-1927).”, JAMA 191: 494-5, 1965, 1965 Feb 8, PMID:14238036, <http://www.ncbi.nlm.nih.gov/pubmed/14238036>
- GAMBAROGLU, K (1963), “[WILLEM EINTHOVEN (1860-1927).]”, Klinicheskaia meditsina 41: 154-6, 1963 Sep, PMID:14090830, <http://www.ncbi.nlm.nih.gov/pubmed/14090830>
- WIGGERS, C J (1961), “Willem EINTHOVEN (1860-1927). Some facets of his life and work.”, Circ. Res. 9: 225-34, 1961 Mar, PMID:13785174, <http://www.ncbi.nlm.nih.gov/pubmed/13785174>
- GOTTLIEB, L S (1961), “Willem EINTHOVEN, M.D., Ph.D., 1860-1927. Centenary of the father of electrocardiography.”, Arch. Intern. Med. 107: 447-9, 1961 Mar, PMID:13707441, <http://www.ncbi.nlm.nih.gov/pubmed/13707441>
- GIRAUD, G (1961), “[Willem EINTHOVEN. Nobel Prize in Medicine.]”, Montpellier médical 59: 189-94, 1961 Mar, PMID:13705673, <http://www.ncbi.nlm.nih.gov/pubmed/13705673>
- NYLIN, G (1954), “Willem Einthoven. Address given at the Einthoven Commemoration Festival, Leyden, December 1953.”, Cardiologia 24 (5): 311-4, 1954, PMID:13182673, <http://www.ncbi.nlm.nih.gov/pubmed/13182673>
- Williams (1928), “WILLEM EINTHOVEN.”, Science 67 (1740): 456-458, 1928 May 4, PMID:17837835, doi:10.1126/science.67.1740.456, <http://www.ncbi.nlm.nih.gov/pubmed/17837835>
- Nobel Lectures, Physiology or Medicine 1922-1941, Elsevier Publishing Company, Amsterdam, 1965.
- Snellen, Herman Adrianus (1995). Willem Einthoven (1860-1927) Father of Electrocardiography, Life and Work, Ancestors and Contemporaries. Dordrecht: Kluwer Academic Publishers. ISBN 0-7923-3274-1.
- Shouldice RB, Bass G (2002). "From Bench to Bedside - Developments in Electrocardiology". The Engineers Journal, Institution of Engineers of Ireland 56 (4): 47-9.
[edit] External links
- The Einthoven Foundation Cardiology Information Portal Historical pictures
- Nobel prize citation
- Einthoven's triangle
- Bibliography in the Virtual Laboratory of the Max Planck Institute for the History of Science
- Museum Boerhaave Negen Nederlandse Nobelprijswinnaars
- A.M. Luyendijk-Elshout, Einthoven, Willem (1860-1927), in Biografisch Woordenboek van Nederland.
- Biography Willem Einthoven (1860-1927) at the National Library of the Netherlands
- Willem Einthoven (1860–1927): Father of electrocardiography.Moukabary, T. Cardiology Journal. 2007, Vol. 14, No. 3, pp. 316–317 Copyright © 2007 Via Medical ISSN 1897–559.
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