WAPAL

From Wikipedia, the free encyclopedia


Wings apart-like homolog (Drosophila)
Identifiers
Symbol(s) WAPAL; FOE; KIAA0261; WAPL
External IDs OMIM: 610754 MGI2675859 HomoloGene41002
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 23063 218914
Ensembl ENSG00000062650 ENSMUSG00000041408
Uniprot Q7Z5K2 Q65Z40
Refseq NM_015045 (mRNA)
NP_055860 (protein)
NM_001004436 (mRNA)
NP_001004436 (protein)
Location Chr 10: 88.18 - 88.27 Mb Chr 14: 33.5 - 33.58 Mb
Pubmed search [1] [2]

Wings apart-like homolog (Drosophila), also known as WAPAL, is a human gene.[1]


[edit] References

[edit] Further reading

  • Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.". DNA Res. 3 (5): 321-9, 341-54. PMID 9039502. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Oikawa K, Ohbayashi T, Kiyono T, et al. (2004). "Expression of a novel human gene, human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression.". Cancer Res. 64 (10): 3545-9. doi:10.1158/0008-5472.CAN-03-3822. PMID 15150110. 
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054. 
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315-23. doi:10.1101/gr.2122004. PMID 15231747. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093-101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747. 
  • Kwiatkowski BA, Ragoczy T, Ehly J, Schubach WH (2004). "Identification and cloning of a novel chromatin-associated protein partner of Epstein-Barr nuclear protein 2.". Exp. Cell Res. 300 (1): 223-33. doi:10.1016/j.yexcr.2004.06.028. PMID 15383329. 
  • Kuroda M, Oikawa K, Ohbayashi T, et al. (2005). "A dioxin sensitive gene, mammalian WAPL, is implicated in spermatogenesis.". FEBS Lett. 579 (1): 167-72. doi:10.1016/j.febslet.2004.11.070. PMID 15620708. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Gandhi R, Gillespie PJ, Hirano T (2007). "Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase.". Curr. Biol. 16 (24): 2406-17. doi:10.1016/j.cub.2006.10.061. PMID 17112726. 
  • Kueng S, Hegemann B, Peters BH, et al. (2007). "Wapl controls the dynamic association of cohesin with chromatin.". Cell 127 (5): 955-67. doi:10.1016/j.cell.2006.09.040. PMID 17113138. 
  • Ohbayashi T, Oikawa K, Yamada K, et al. (2007). "Unscheduled overexpression of human WAPL promotes chromosomal instability.". Biochem. Biophys. Res. Commun. 356 (3): 699-704. doi:10.1016/j.bbrc.2007.03.037. PMID 17382297.