VPS52

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Vacuolar protein sorting 52 homolog (S. cerevisiae)
Identifiers
Symbol(s) VPS52; ARE1; DKFZp547I194; RP5-1033B10; SAC2; SACM2L; dJ1033B10.5
External IDs OMIM: 603443 MGI: 1330304 HomoloGene: 5756
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 6293 224705
Ensembl ENSG00000112478 ENSMUSG00000024319
Uniprot Q8N1B4 Q3V3A4
Refseq NM_022553 (mRNA)
NP_072047 (protein)		 XM_001001424 (mRNA)
XP_001001424 (protein)
Location Chr 6: 33.33 - 33.35 Mb Chr 17: 33.57 - 33.58 Mb
Pubmed search [1] [2]

Vacuolar protein sorting 52 homolog (S. cerevisiae), also known as VPS52, is a human gene.[1]

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.[1]

[edit] References

  1. ^ a b Entrez Gene: VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae).

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Walter L, Günther E (1998). "Identification of a novel highly conserved gene in the centromeric part of the major histocompatibility complex.". Genomics 52 (3): 298–304. doi:10.1006/geno.1998.5463. PMID 9790748. 
  • Stephens R, Horton R, Humphray S, et al. (1999). "Gene organisation, sequence variation and isochore structure at the centromeric boundary of the human MHC.". J. Mol. Biol. 291 (4): 789–99. doi:10.1006/jmbi.1999.3004. PMID 10452889. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Liewen H, Meinhold-Heerlein I, Oliveira V, et al. (2005). "Characterization of the human GARP (Golgi associated retrograde protein) complex.". Exp. Cell Res. 306 (1): 24–34. doi:10.1016/j.yexcr.2005.01.022. PMID 15878329. 
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