VPS36

From Wikipedia, the free encyclopedia

Vacuolar protein sorting 36 homolog (S. cerevisiae)

PDB rendering based on 2dx5.

Available structures: 2dx5, 2hth

Identifiers

Symbol(s)

VPS36; C13orf9; CGI-145; DKFZp781E0871; EAP45

External IDs

MGI: 1917410 HomoloGene: 9374

Gene ontology
Molecular Function:	• lipid binding • ubiquitin binding
Cellular Component:	• nucleus • lysosome • late endosome
Biological Process:	• transcription • regulation of transcription, DNA-dependent • protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_016075 (mRNA)
NP_057159 (protein)

NM_027338 (mRNA)
NP_081614 (protein)

Location

Chr 13: 51.88 - 51.92 Mb

Chr 8: 23.66 - 23.68 Mb

Pubmed search

[1]

[2]

Vacuolar protein sorting 36 homolog (S. cerevisiae), also known as VPS36, is a human gene.^[1]

[edit] References

^ Entrez Gene: VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae).

[edit] Further reading

Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.". Genome Res. 10 (5): 703-13. PMID 10810093.
Kamura T, Burian D, Khalili H, et al. (2001). "Cloning and characterization of ELL-associated proteins EAP45 and EAP20. a role for yeast EAP-like proteins in regulation of gene expression by glucose.". J. Biol. Chem. 276 (19): 16528-33. doi:10.1074/jbc.M010142200. PMID 11278625.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
von Schwedler UK, Stuchell M, Müller B, et al. (2003). "The protein network of HIV budding.". Cell 114 (6): 701-13. PMID 14505570.
Martin-Serrano J, Yarovoy A, Perez-Caballero D, et al. (2003). "Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins.". Proc. Natl. Acad. Sci. U.S.A. 100 (21): 12414-9. doi:10.1073/pnas.2133846100. PMID 14519844.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522-8. doi:10.1038/nature02379. PMID 15057823.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Slagsvold T, Aasland R, Hirano S, et al. (2005). "Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain.". J. Biol. Chem. 280 (20): 19600-6. doi:10.1074/jbc.M501510200. PMID 15755741.
Bowers K, Piper SC, Edeling MA, et al. (2006). "Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.". J. Biol. Chem. 281 (8): 5094-105. doi:10.1074/jbc.M508632200. PMID 16371348.
Alam SL, Langelier C, Whitby FG, et al. (2007). "Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.". Nat. Struct. Mol. Biol. 13 (11): 1029-30. doi:10.1038/nsmb1160. PMID 17057716.