Vincamine
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Vincamine
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| Systematic (IUPAC) name | |
| (3α,14β,16α)-14,15-dihydro- 14-hydroxyeburnamenine-14-carboxylic acid methyl ester |
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| Identifiers | |
| CAS number | |
| ATC code | C04 |
| PubChem | |
| Chemical data | |
| Formula | C21H26N2O3 |
| Mol. mass | 354.44 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Vincamine is a peripheral vasodilator that increases blood flow to the brain. It is an indole alkaloid (specifically a tryptamine) found in the leaves of Vinca minor, comprising about 25-65% of the indole alkaloids found in Vinca minor by weight. It is also found in the species Catharanthus roseus. It can be synthesized from related alkaloids.
Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes.
[edit] References
- ^ Cook, P; James, I (Dec. 24, 1981). "Cerebral vasodilators". N Engl J Med. 305 (26): 1560–1564. PMID 7031468.
- ^ "Indole Alkaloids". Ullmann's Encyclopedia of Industrial Chemistry, Fifth Edition. (1985). Wiley-VCH. 393. ISBN: 3-527-20100-9.
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