Talk:Vascular endothelial growth factor
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Anyone know what size(s) VEGF A would run at on an SDS-PAGE gel under reducing conditions? 21 kDa reduced, 42 non-reduced
Who first discovered it?
- From Online 'Mendelian Inheritance in Man' (OMIM) 192240: it was first discovered by Ferrara & Henzel in 1989. See PMID 2735925 for the abstract of that study. JFW | T@lk 14:59, 19 September 2005 (UTC)
- Have to correct this. It was first discovered by Senger et al. in 1983 and originally described as EPF (Endothelial Permeability Factor) for its effects on increasing the permeability of vascular endothelium. See PMID 6823562 for an abstract.
[edit] Classification
Right now there are two alternative classifications, which is confusing. Is it possible that the "alternative classification" actually is the classification of VEGF-A? It might have been left here, although what was called VEGF historically is now called VEGF-A. Mikael Häggström (talk) 14:00, 30 January 2008 (UTC)
