Valine-3-methyl-2-oxovalerate transaminase

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In enzymology, a valine-3-methyl-2-oxovalerate transaminase (EC 2.6.1.32) is an enzyme that catalyzes the chemical reaction

L-valine + (S)-3-methyl-2-oxopentanoate 3-methyl-2-oxobutanoate + L-isoleucine

Thus, the two substrates of this enzyme are L-valine and (S)-3-methyl-2-oxopentanoate, whereas its two products are 3-methyl-2-oxobutanoate and L-isoleucine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase. Other names in common use include valine-isoleucine transaminase, valine-3-methyl-2-oxovalerate aminotransferase, alanine-valine transaminase, valine-2-keto-methylvalerate aminotransferase, and valine-isoleucine aminotransferase.

[edit] References

• IUBMB entry for 2.6.1.32
• BRENDA references for 2.6.1.32 (Recommended.)
• PubMed references for 2.6.1.32
• PubMed Central references for 2.6.1.32
• Google Scholar references for 2.6.1.32
• Kagan ZS, Dronov AS and Kretovich VL (1968). "[Some properties of valine-isoleucine- and valine-glutamate-aminotransferases of pea sprouts.]". Dokl. Akad. Nauk S.S.S.R. 179: 1236–1239. 

[edit] External links

The CAS registry number for this enzyme class is 9023-14-7.

• IUBMB entry for 2.6.1.32

• KEGG entry for 2.6.1.32

• BRENDA entry for 2.6.1.32

• NiceZyme view of 2.6.1.32

• EC2PDB: PDB structures for 2.6.1.32

• PRIAM entry for 2.6.1.32

• PUMA2 entry for 2.6.1.32

• IntEnz: Integrated Enzyme entry for 2.6.1.32

• MetaCyc entry for 2.6.1.32

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047301: valine-3-methyl-2-oxovalerate transaminase

• AMIGO entry for GO code 0047301: valine-3-methyl-2-oxovalerate transaminase