Talk:Valvular heart disease

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In March 29, 2007, pergolide, a dopamine agonist used in treatment of Parkinson's disease and also off label for Restless legs syndrome (RLS), was withdrawn from the US market due to implication in valvular heart disease [1]. The withdrawal was based on findings published in New England Journal of Medicine, confirming previous reports associating pergolide with increased risk of regurgitation of the mitral valve, tricuspid valve, and aortic valve of the heart. Cabergoline, a similar ergot-derived dopamine agonist, is still marketed in EU.

Ergot derivatives (ergotamines) have been implicated in fibrosis not only of the heart valves but also of the pleura and retroperitoneum [2] and possibly other locations.

This is a typical Wikipedia phenomenon - just because this discovery was made after 2001 it is mentioned with massive prominence in an article that is otherwise nothing more than a list. I am removing it temporarily per WP:WEIGHT considerations until the page is more mature. JFW | T@lk 11:52, 13 January 2008 (UTC)

[edit] European guidelines

... are a lot shorter - just 39 pages. doi:10.1093/eurhartj/ehl428 JFW | T@lk 12:37, 21 January 2008 (UTC)