UTX (gene)

From Wikipedia, the free encyclopedia


Ubiquitously transcribed tetratricopeptide repeat, X chromosome
Identifiers
Symbol(s) UTX; DKFZp686A03225; MGC141941; bA386N14.2
External IDs OMIM: 300128 MGI: 1095419 HomoloGene: 7586
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 7403 22289
Ensembl ENSG00000147050 ENSMUSG00000037369
Uniprot O15550 Q3TNW2
Refseq NM_021140 (mRNA)
NP_066963 (protein)		 NM_009483 (mRNA)
NP_033509 (protein)
Location Chr X: 44.62 - 44.86 Mb Chr X: 17.32 - 17.44 Mb
Pubmed search [1] [2]

Ubiquitously transcribed tetratricopeptide repeat, X chromosome, also known as UTX, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: UTX ubiquitously transcribed tetratricopeptide repeat, X chromosome.

[edit] Further reading

  • Lahn BT, Page DC (1997). "Functional coherence of the human Y chromosome.". Science 278 (5338): 675–80. PMID 9381176. 
  • Greenfield A, Carrel L, Pennisi D, et al. (1998). "The UTX gene escapes X inactivation in mice and humans.". Hum. Mol. Genet. 7 (4): 737–42. PMID 9499428. 
  • Grbavec D, Lo R, Liu Y, et al. (1999). "Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms.". Biochem. J. 337 ( Pt 1): 13–7. PMID 9854018. 
  • Foresta C, Ferlin A, Moro E (2000). "Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility.". Hum. Mol. Genet. 9 (8): 1161–9. PMID 10767340. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Agate RJ, Choe M, Arnold AP (2004). "Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.". Mol. Biol. Evol. 21 (2): 384–96. doi:10.1093/molbev/msh027. PMID 14660691. 
  • Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747. 
  • Gerrard DT, Filatov DA (2005). "Positive and negative selection on mammalian Y chromosomes.". Mol. Biol. Evol. 22 (6): 1423–32. doi:10.1093/molbev/msi128. PMID 15758204. 
  • Cho YW, Hong T, Hong S, et al. (2007). "PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.". J. Biol. Chem. 282 (28): 20395–406. doi:10.1074/jbc.M701574200. PMID 17500065. 
  • Agger K, Cloos PA, Christensen J, et al. (2007). "UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.". Nature 449 (7163): 731–4. doi:10.1038/nature06145. PMID 17713478. 
  • Lee MG, Villa R, Trojer P, et al. (2007). "Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.". Science 318 (5849): 447–50. doi:10.1126/science.1149042. PMID 17761849. 
  • Lan F, Bayliss PE, Rinn JL, et al. (2007). "A histone H3 lysine 27 demethylase regulates animal posterior development.". Nature 449 (7163): 689–94. doi:10.1038/nature06192. PMID 17851529. 
  • Hong S, Cho YW, Yu LR, et al. (2008). "Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases.". Proc. Natl. Acad. Sci. U.S.A. 104 (47): 18439–44. doi:10.1073/pnas.0707292104. PMID 18003914. 
 This article on a gene on the X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.