USP39

From Wikipedia, the free encyclopedia

Ubiquitin specific peptidase 39

Identifiers

USP39; SAD1; CGI-21; HSPC332; MGC75069

External IDs

Gene ontology
Molecular Function:	• nucleic acid binding • ubiquitin thiolesterase activity • zinc ion binding • metal ion binding
Cellular Component:	• intracellular • nucleus
Biological Process:	• spliceosome assembly • mRNA processing • ubiquitin-dependent protein catabolic process • RNA splicing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006590 (mRNA)
NP_006581 (protein)

NM_138592 (mRNA)
NP_613058 (protein)

Location

Chr 2: 85.7 - 85.73 Mb

Chr 6: 72.25 - 72.27 Mb

Pubmed search

[1]

[2]

Ubiquitin specific peptidase 39, also known as USP39, is a human gene.^[1]

[edit] References

^ Entrez Gene: USP39 ubiquitin specific peptidase 39.

[edit] Further reading

Puente XS, Sánchez LM, Overall CM, López-Otín C (2003). "Human and mouse proteases: a comparative genomic approach.". Nat. Rev. Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Lygerou Z, Christophides G, Séraphin B (1999). "A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing.". Mol. Cell. Biol. 19 (3): 2008–20. PMID 10022888.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.". Genome Res. 10 (5): 703–13. PMID 10810093.
Makarova OV, Makarov EM, Lührmann R (2001). "The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes.". EMBO J. 20 (10): 2553–63. doi:10.1093/emboj/20.10.2553. PMID 11350945.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.