USP13

From Wikipedia, the free encyclopedia

Ubiquitin specific peptidase 13 (isopeptidase T-3)

Identifiers

USP13; ISOT3; IsoT-3

External IDs

OMIM: 603591 MGI: 1919857 HomoloGene: 68372

Gene ontology
Molecular Function:	• cysteine-type endopeptidase activity • ubiquitin thiolesterase activity • zinc ion binding • metal ion binding
Biological Process:	• ubiquitin-dependent protein catabolic process • ubiquitin cycle

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_003940 (mRNA)
NP_003931 (protein)

NM_001013024 (mRNA)
NP_001013042 (protein)

Location

Chr 3: 180.85 - 180.98 Mb

Chr 3: 33.01 - 33.13 Mb

Pubmed search

[1]

[2]

Ubiquitin specific peptidase 13 (isopeptidase T-3), also known as USP13, is a human gene.^[1]

[edit] References

^ Entrez Gene: USP13 ubiquitin specific peptidase 13 (isopeptidase T-3).

[edit] Further reading

D'Andrea A, Pellman D (1999). "Deubiquitinating enzymes: a new class of biological regulators.". Crit. Rev. Biochem. Mol. Biol. 33 (5): 337-52. PMID 9827704.
Puente XS, Sánchez LM, Overall CM, López-Otín C (2003). "Human and mouse proteases: a comparative genomic approach.". Nat. Rev. Genet. 4 (7): 544-58. doi:10.1038/nrg1111. PMID 12838346.
Timms KM, Ansari-Lari MA, Morris W, et al. (1998). "The genomic organization of Isopeptidase T-3 (ISOT-3), a new member of the ubiquitin specific protease family (UBP).". Gene 217 (1-2): 101-6. PMID 9841226.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788-95. PMID 11076863.
McElhinny AS, Kakinuma K, Sorimachi H, et al. (2002). "Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1.". J. Cell Biol. 157 (1): 125-36. doi:10.1083/jcb.200108089. PMID 11927605.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMID 15231748.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136-44. doi:10.1101/gr.2576704. PMID 15489336.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957-68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMID 16381901.