Uronolactonase

From Wikipedia, the free encyclopedia

In enzymology, an uronolactonase (EC 3.1.1.19) is an enzyme that catalyzes the chemical reaction

D-glucurono-6,2-lactone + H₂O D-glucuronate

Thus, the two substrates of this enzyme are D-glucurono-6,2-lactone and H₂O, whereas its product is D-glucuronate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is D-glucurono-6,2-lactone lactonohydrolase. This enzyme is also called glucuronolactonase. This enzyme participates in ascorbate and aldarate metabolism.

[edit] References

• IUBMB entry for 3.1.1.19
• BRENDA references for 3.1.1.19 (Recommended.)
• PubMed references for 3.1.1.19
• PubMed Central references for 3.1.1.19
• Google Scholar references for 3.1.1.19
• Winkelman J and Lehninger AL (1958). "Aldono- and uronolactonase of animal tissues". J. Biol. Chem. 233: 794–799. 

[edit] External links

The CAS registry number for this enzyme class is 9025-93-8.

• IUBMB entry for 3.1.1.19

• KEGG entry for 3.1.1.19

• BRENDA entry for 3.1.1.19

• NiceZyme view of 3.1.1.19

• EC2PDB: PDB structures for 3.1.1.19

• PRIAM entry for 3.1.1.19

• PUMA2 entry for 3.1.1.19

• IntEnz: Integrated Enzyme entry for 3.1.1.19

• MetaCyc entry for 3.1.1.19

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050389: uronolactonase

• AMIGO entry for GO code 0050389: uronolactonase