Uroguanylin
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guanylate cyclase activator 2B (uroguanylin)
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| Identifiers | |
| Symbol | GUCA2B |
| Entrez | 2981 |
| HUGO | 4683 |
| OMIM | 601271 |
| RefSeq | NM_007102 |
| UniProt | Q16661 |
| Other data | |
| Locus | Chr. 1 p34-p33 |
Uroguanylin is a 16 amino acid peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia.
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