UQCRH

From Wikipedia, the free encyclopedia


Ubiquinol-cytochrome c reductase hinge protein
PDB rendering based on 1bcc.
Available structures: 1bcc, 1be3, 1bgy, 1l0l, 1l0n, 1ntk, 1ntm, 1ntz, 1nu1, 1pp9, 1ppj, 1qcr, 1sqb, 1sqp, 1sqq, 1sqv, 1sqx, 2a06, 2bcc, 2fyu, 3bcc
Identifiers
Symbol(s) UQCRH; MGC111572
External IDs MGI1913826 HomoloGene48393
Orthologs
Human Mouse
Entrez 7388 66576
Ensembl n/a ENSMUSG00000063882
Uniprot n/a Q8BMU6
Refseq NM_006004 (mRNA)
NP_005995 (protein)
NM_025641 (mRNA)
NP_079917 (protein)
Location n/a Chr 4: 115.56 - 115.57 Mb
Pubmed search [1] [2]

Ubiquinol-cytochrome c reductase hinge protein, also known as UQCRH, is a human gene.[1]


[edit] References

[edit] Further reading

  • Ohta S, Goto K, Arai H, Kagawa Y (1988). "An extremely acidic amino-terminal presequence of the precursor for the human mitochondrial hinge protein.". FEBS Lett. 226 (1): 171–5. PMID 2826252. 
  • Liu AY, Bradner RC (1993). "Elevated expression of the human mitochondrial hinge protein gene in cancer.". Cancer Res. 53 (11): 2460–5. PMID 7684318. 
  • Kato S, Sekine S, Oh SW, et al. (1995). "Construction of a human full-length cDNA bank.". Gene 150 (2): 243–50. PMID 7821789. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Modena P, Testi MA, Facchinetti F, et al. (2003). "UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.". Oncogene 22 (29): 4586–93. doi:10.1038/sj.onc.1206472. PMID 12881716. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wen JJ, Garg N (2005). "Oxidative modification of mitochondrial respiratory complexes in response to the stress of Trypanosoma cruzi infection.". Free Radic. Biol. Med. 37 (12): 2072–81. doi:10.1016/j.freeradbiomed.2004.09.011. PMID 15544925. 
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.