UBP1

From Wikipedia, the free encyclopedia

Upstream binding protein 1 (LBP-1a)

Identifiers

UBP1; DKFZp686L1745; LBP-1B; LBP-1a; LBP1A; LBP1B

External IDs

OMIM: 609784 MGI: 104889 HomoloGene: 8435

Gene ontology
Molecular Function:	• transcription factor activity • transcription corepressor activity • specific transcriptional repressor activity
Cellular Component:	• nucleus
Biological Process:	• angiogenesis • transcription • regulation of transcription from RNA polymerase II promoter • negative regulation of transcription • viral genome replication

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014517 (mRNA)
NP_055332 (protein)

XM_980605 (mRNA)
XP_985699 (protein)

Location

Chr 3: 33.4 - 33.46 Mb

Chr 9: 113.78 - 113.83 Mb

Pubmed search

[1]

[2]

Upstream binding protein 1 (LBP-1a), also known as UBP1, is a human gene.^[1]

[edit] References

^ Entrez Gene: UBP1 upstream binding protein 1 (LBP-1a).

[edit] Further reading

Kato H, Horikoshi M, Roeder RG (1991). "Repression of HIV-1 transcription by a cellular protein.". Science 251 (5000): 1476–9. PMID 2006421.
Parada CA, Yoon JB, Roeder RG (1995). "A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro.". J. Biol. Chem. 270 (5): 2274–83. PMID 7836461.
Yoon JB, Li G, Roeder RG (1994). "Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro.". Mol. Cell. Biol. 14 (3): 1776–85. PMID 8114710.
Huang N, Miller WL (2000). "Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc.". J. Biol. Chem. 275 (4): 2852–8. PMID 10644752.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Zhao H, Li J, Jiang L (2004). "Inhibition of HIV-1 TAR RNA-Tat peptide complexation using poly(acrylic acid).". Biochem. Biophys. Res. Commun. 320 (1): 95–9. doi:10.1016/j.bbrc.2004.05.148. PMID 15207707.
Huang N, Miller WL (2005). "LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells.". Mol. Endocrinol. 19 (2): 409–20. doi:10.1210/me.2004-0086. PMID 15471945.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.