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| U7 small nuclear RNA |
 |
| Type: |
Gene; snRNA; |
| 2° structure: |
Predicted; PFOLD; Griffiths-Jones SR |
| Seed alignment: |
Griffiths-Jones SR |
| Avg length: |
49.0 nucleotides |
| Avg identity: |
69% |
|
The U7 small nuclear RNA (U7 snRNP) is an RNA molecule involved in the splicing of animal histone pre-mRNAs, which are spliced by a different mechanism than nuclear pre-mRNAs and self-splicing introns. The 5' end of U7 RNA is thought to base-pair to a conserved spacer element downstream of the cleavage site in histone pre-mRNA.
[edit] References
- Spycher, C; Streit A, Stefanovic B, Albrecht D, Koning TH, Schumperli D (1994). "3' end processing of mouse histone pre-mRNA: evidence for additional base-pairing between U7 snRNA and pre-mRNA". Nucleic Acids Res 22: 4023–4030. doi:10.1093/nar/22.20.4023. PMID 7937126.
- Mowry, KL; Steitz JA (1987). "Identification of the human U7 snRNP as one of several factors involved in the 3' end maturation of histone premessenger RNA's". Science 238: 1682–1687. doi:10.1126/science.2825355. PMID 2825355.
[edit] External links
