TXNDC2

From Wikipedia, the free encyclopedia

Thioredoxin domain containing 2 (spermatozoa)

Identifiers

TXNDC2; DKFZp434H0311; MGC35026; SPTRX

External IDs

Gene ontology
Molecular Function:	• thioredoxin-disulfide reductase activity • protein disulfide oxidoreductase activity • thiol-disulfide exchange intermediate activity
Cellular Component:	• cytoplasm • microtubule-based flagellum
Biological Process:	• thioredoxin pathway • protein thiol-disulfide exchange • multicellular organismal development • spermatogenesis • cell differentiation • cell redox homeostasis

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_032243 (mRNA)
NP_115619 (protein)

NM_153519 (mRNA)
NP_705739 (protein)

Location

n/a

Chr 17: 65.54 - 65.54 Mb

Pubmed search

[1]

[2]

Thioredoxin domain containing 2 (spermatozoa), also known as TXNDC2, is a human gene.^[1]

[edit] References

^ Entrez Gene: TXNDC2 thioredoxin domain containing 2 (spermatozoa).

[edit] Further reading

Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Jiménez A, Johansson C, Ljung J, et al. (2002). "Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity.". FEBS Lett. 530 (1-3): 79-84. PMID 12387870.
Sadek CM, Damdimopoulos AE, Pelto-Huikko M, et al. (2002). "Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells.". Genes Cells 6 (12): 1077-90. PMID 11737268.
Miranda-Vizuete A, Ljung J, Damdimopoulos AE, et al. (2001). "Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa.". J. Biol. Chem. 276 (34): 31567-74. doi:10.1074/jbc.M101760200. PMID 11399755.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166.