TSPYL2

From Wikipedia, the free encyclopedia

TSPY-like 2

Identifiers

TSPYL2; CINAP; CDA1; CTCL; DENTT; HRIHFB2216; SE20-4

External IDs

OMIM: 300564 MGI: 106244 HomoloGene: 11140

Gene ontology
Molecular Function:	• rDNA binding • protein binding
Cellular Component:	• nucleus • nucleolus
Biological Process:	• nucleosome assembly • negative regulation of DNA replication • regulation of signal transduction • negative regulation of cell growth • negative regulation of progression through cell cycle • regulation of protein kinase activity • cell division

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

XM_001128695 (mRNA)
XP_001128695 (protein)

NM_029836 (mRNA)
NP_084112 (protein)

Location

Chr X: 53.13 - 53.13 Mb

Chr X: 147.68 - 147.68 Mb

Pubmed search

[1]

[2]

TSPY-like 2, also known as TSPYL2, is a human gene.^[1]

[edit] References

^ Entrez Gene: TSPYL2 TSPY-like 2.

[edit] Further reading

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788-95. PMID 11076863.
Eichmuller S, Usener D, Dummer R, et al. (2001). "Serological detection of cutaneous T-cell lymphoma-associated antigens.". Proc. Natl. Acad. Sci. U.S.A. 98 (2): 629-34. doi:10.1073/pnas.021386498. PMID 11149944.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166.
Ozbun LL, You L, Kiang S, et al. (2001). "Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily.". Genomics 73 (2): 179-93. doi:10.1006/geno.2001.6505. PMID 11318608.
Chai Z, Sarcevic B, Mawson A, Toh BH (2001). "SET-related cell division autoantigen-1 (CDA1) arrests cell growth.". J. Biol. Chem. 276 (36): 33665-74. doi:10.1074/jbc.M007681200. PMID 11395479.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Wang GS, Hong CJ, Yen TY, et al. (2004). "Transcriptional modification by a CASK-interacting nucleosome assembly protein.". Neuron 42 (1): 113-28. PMID 15066269.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136-44. doi:10.1101/gr.2576704. PMID 15489336.
Santama N, Ogg SC, Malekkou A, et al. (2006). "Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus.". J. Biol. Chem. 280 (43): 36429-41. doi:10.1074/jbc.M501982200. PMID 16079131.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMID 16381901.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801-14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Radke JR, Donald RG, Eibs A, et al. (2006). "Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development.". PLoS Pathog. 2 (10): e105. doi:10.1371/journal.ppat.0020105. PMID 17069459.
Tu Y, Wu W, Wu T, et al. (2007). "Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways.". J. Biol. Chem. 282 (16): 11722-31. doi:10.1074/jbc.M609623200. PMID 17317670.