TSPY1

From Wikipedia, the free encyclopedia

Testis specific protein, Y-linked 1

Identifiers

TSPY1; DYS14; TSPY; pJA923; MGC103998; TSPYQ1

External IDs

Gene ontology
Molecular Function:	• molecular_function
Cellular Component:	• cellular_component • nucleus
Biological Process:	• nucleosome assembly • multicellular organismal development • spermatogenesis • gonadal mesoderm development • sex differentiation • cell proliferation • cell differentiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_003308 (mRNA)
NP_003299 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr Y: 6.17 - 6.18 Mb

n/a

Pubmed search

[1]

n/a

Testis specific protein, Y-linked 1, also known as TSPY1, is a human gene.^[1]

[edit] References

^ Entrez Gene: TSPY1 Testis specific protein, Y-linked 1.

[edit] Further reading

Chandley AC, Cooke HJ (1995). "Human male fertility--Y-linked genes and spermatogenesis.". Hum. Mol. Genet. 3 Spec No: 1449-52. PMID 7849736.
Vogel T, Schmidtke J (1998). "Structure and function of TSPY, the Y-chromosome gene coding for the "testis-specific protein".". Cytogenet. Cell Genet. 80 (1-4): 209-13. PMID 9678360.
Lau YF (2000). "Gonadoblastoma, testicular and prostate cancers, and the TSPY gene.". Am. J. Hum. Genet. 64 (4): 921-7. PMID 10090875.
Zhang JS, Yang-Feng TL, Muller U, et al. (1993). "Molecular isolation and characterization of an expressed gene from the human Y chromosome.". Hum. Mol. Genet. 1 (9): 717-26. PMID 1284595.
Arnemann J, Jakubiczka S, Thüring S, Schmidtke J (1992). "Cloning and sequence analysis of a human Y-chromosome-derived, testicular cDNA, TSPY.". Genomics 11 (1): 108-14. PMID 1765369.
Arnemann J, Epplen JT, Cooke HJ, et al. (1988). "A human Y-chromosomal DNA sequence expressed in testicular tissue.". Nucleic Acids Res. 15 (21): 8713-24. PMID 3479749.
Manz E, Schnieders F, Brechlin AM, Schmidtke J (1993). "TSPY-related sequences represent a microheterogeneous gene family organized as constitutive elements in DYZ5 tandem repeat units on the human Y chromosome.". Genomics 17 (3): 726-31. doi:10.1006/geno.1993.1393. PMID 8244388.
Kim HS, Takenaka O (1996). "A comparison of TSPY genes from Y-chromosomal DNA of the great apes and humans: sequence, evolution, and phylogeny.". Am. J. Phys. Anthropol. 100 (3): 301-9. doi:10.1002/(SICI)1096-8644(199607)100:3<301::AID-AJPA1>3.0.CO;2-X. PMID 8798990.
Schnieders F, Dörk T, Arnemann J, et al. (1997). "Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues.". Hum. Mol. Genet. 5 (11): 1801-7. PMID 8923009.
Vogt PH, Affara N, Davey P, et al. (1998). "Report of the Third International Workshop on Y Chromosome Mapping 1997. Heidelberg, Germany, April 13-16, 1997.". Cytogenet. Cell Genet. 79 (1-2): 1-20. PMID 9533010.
Vogel T, Dittrich O, Mehraein Y, et al. (1998). "Murine and human TSPYL genes: novel members of the TSPY-SET-NAP1L1 family.". Cytogenet. Cell Genet. 81 (3-4): 265-70. PMID 9730615.
Lau YF, Zhang J (2000). "Expression analysis of thirty one Y chromosome genes in human prostate cancer.". Mol. Carcinog. 27 (4): 308-21. PMID 10747295.
Ratti A, Stuppia L, Gatta V, et al. (2000). "Characterization of a new TSPY gene family member in Yq (TSPYq1).". Cytogenet. Cell Genet. 88 (1-2): 159-62. PMID 10773691.
Dechend F, Williams G, Skawran B, et al. (2001). "TSPY variants in six loci on the human Y chromosome.". Cytogenet. Cell Genet. 91 (1-4): 67-71. PMID 11173833.
Lau Y, Chou P, Iezzoni J, et al. (2001). "Expression of a candidate gene for the gonadoblastoma locus in gonadoblastoma and testicular seminoma.". Cytogenet. Cell Genet. 91 (1-4): 160-4. PMID 11173850.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Krick R, Jakubiczka S, Arnemann J (2003). "Expression, alternative splicing and haplotype analysis of transcribed testis specific protein (TSPY) genes.". Gene 302 (1-2): 11-9. PMID 12527192.